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Progressive nodular histiocytosis in a child with a hypothalamic tumour

✍ Scribed by S.J. Beswick; J.M.W. Kirk; K. Bradshaw; D.S.A. Sanders; C. Moss


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
926 KB
Volume
146
Category
Article
ISSN
0007-0963

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✦ Synopsis


We report a 13-year-old girl with multiple cutaneous histiocytic lesions, precocious puberty, growth hormone deficiency and a hypothalamic tumour. We conclude that she has progressive nodular histiocytosis, but this case illustrates the difficulty in differentiating the type II histiocytoses.


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## Abstract Neuroblastoma occurring as a disseminated disease in children has a poor prognosis. Haematogenous metastases usually involve the marrow, bone, liver and skin. A second neoplasm may also develop. We describe a child with retroperitoneal neuroblastoma (stage 3) who developed a nodular mas