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Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

✍ Scribed by Chiara Zuccato; Daniel Liber; Catarina Ramos; Alessia Tarditi; Dorotea Rigamonti; Marzia Tartari; Marta Valenza; Elena Cattaneo


Book ID
119346175
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
265 KB
Volume
52
Category
Article
ISSN
1043-6618

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Increased GABAergic function in mouse mo
✍ Carlos Cepeda; Amaal J. Starling; Nanping Wu; Oanh K. Nguyen; Besim Uzgil; Takah πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 559 KB

## Abstract Huntington's disease (HD) is characterized by loss of striatal γ‐aminobutyric acid (GABA)ergic medium‐sized spiny projection neurons (MSSNs), whereas some classes of striatal interneurons are relatively spared. Striatal interneurons provide most of the inhibitory synaptic input to MSSNs