✦ LIBER ✦

Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease

✍ Scribed by Tyisha Hathorn; Abigail Snyder-Keller; Anne Messer

Book ID: 113812525
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 872 KB
Volume: 41
Category: Article
ISSN: 0969-9961
DOI: 10.1016/j.nbd.2010.08.017

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A combination drug therapy improves cogn

A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease

✍ A. Jennifer Morton; Mark J. Hunt; Angela K. Hodges; Paul D. Lewis; Amanda J. Red 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 617 KB

Environmental enrichment ameliorates a m

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome –Mecp2 gene dosage effects and BDNF expression

✍ Mari Kondo; Laura J. Gray; Gregory J. Pelka; John Christodoulou; Patrick P. L. T 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 502 KB

Transgenic expression and activation of

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

✍ Giuseppa Mudò; Johanna Mäkelä; Valentina Di Liberto; Timofey V. Tselykh; Melania 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 745 KB

Gabapentin-lactam, but not gabapentin, r

Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington’s disease

✍ Birgit Zucker; Dagmar E. Ludin; Thomas A. Gerds; Carl H. Lücking; G. Bernhard La 📂 Article 📅 2004 🏛 Springer-Verlag 🌐 English ⚖ 293 KB

High doses of nicotinamide prevent oxida

High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease

✍ Haiqun Jia; Xin Li; Hongxiang Gao; Zhihui Feng; Xuesen Li; Lei Zhao; Xu Jia; Hon 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 287 KB 👁 1 views

## Abstract Nicotinamide, the principal form of niacin (vitamin B3), has been proposed to be neuroprotective in Parkinson's disease. However, the effects and mechanisms of nicotinamide on motor function in animals and on mitochondrial function in cellular systems have not been well studied. We hypo

Exercise improves motor deficits and alt

Exercise improves motor deficits and alters striatal GFAP expression in a 6-OHDA-induced rat model of Parkinson’s disease

✍ Márcio Ferreira Dutra, Mariane Jaeger, Jocemar Ilha, Pedro Ivo Kalil-Gaspar, Sim 📂 Article 📅 2012 🏛 Springer Milan 🌐 English ⚖ 470 KB