Progressive decrease in protein synthesis accuracy induced by streptomycin in Escherichia coli
โ Scribed by BRANSCOMB, E. W.; GALAS, D. J.
- Book ID
- 109694686
- Publisher
- Nature Publishing Group
- Year
- 1975
- Tongue
- English
- Weight
- 395 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/254161a0
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๐ SIMILAR VOLUMES
Peptidyl tRNA hydrolase is an essential enzyme for normal growth inasmuch as a mutant strain of Escherichia coli with a temperature-sensitive hydrolase cannot continue protein synthesis at the non-permissive temperature. In the absence of hydrolase peptidyl tRNA rapidly accumulates. Why peptidyl tRN
In a rifS/rifR heterodiploid strain of E. coli, a 4 minute pulse of rifampicin can induce a prolonged (greater than 60 min) increase in the rate of synthesis of the RNA polymerase subunits, beta and beta'. The application of a constraint on the fidelity of protein synthesis during, but not after, th