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Progress in medicinal chemistry, volume 26. Edited by G. P. Ellis and G. B. West. Elsevier Science Publishers: Amsterdam, 1989. v + 586 pp. 15 × 21 cm. ISBN 0-444-81038-2. $197.50

✍ Scribed by Irach B. Taraporewala

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
287 KB
Volume
79
Category
Article
ISSN
0022-3549

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Progress in medicinal chemistry, vol. 19
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✍ Iris H. Hall 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 138 KB

The integral in Eq. 15 was evaluated numerically by a commonly used integration algorithm (4). Special caution must be taken in applying a loading dose of a nonlinear drug. It may not be desirable to use a loading dose for a drug showing a narrow therapeutic index. However, in certain clinical situ