Progress in Basic and Clinical Immunology

✍ Scribed by Andrzej Mackiewicz, Maciej Kurpisz, Jan Zeromski (auth.), Andrzej Mackiewicz, Maciej Kurpisz, Jan Żeromski (eds.)

• Publisher: Springer US
• Year: 2001
• Tongue: English
• Leaves: 421
• Series: Advances in Experimental Medicine and Biology 495
• Edition: 1
• Category: Library

✦ Synopsis

Progress in Basic and Clinical Immunology is a result of the 14th European Immunology Meeting - EFIS 2000, held in Poznan, Poland, on 23-27 September 2000. EFIS 2000 gathered over 1400 immunologists from all over the world. It was an exceptionally memorable meeting for a number of reasons: 1) it was held in the last year of the century and the millennium, thus provoking conclusions of past achievements of immunology and projections for the future; 2) it was held in Poland, a country that is a symbol of struggle for freedom for a large number of scientists originating from the `Eastern Bloc' countries; and 3) EFIS celebrated its 25th anniversary at this occasion. This comprehensive volume contains 62 chapters grouped into 11 sections: T-cells, Immune Receptors, Antigen Presentation/Dendritic Cells, Cytokines, Immunodeficiencies, Autoimmunity, Allergy/Inflammation, Immunotherapy, Vaccines, Tumor Immunology, and Cancer Immunotherapy.

✦ Table of Contents

Front Matter....Pages i-xvii
Inrtoduction....Pages 1-1
Front Matter....Pages 3-3
CD3-dependent regulation of early TCRβ gene expression in mainstream αβ and NKαβ T cell development....Pages 5-13
Molecular characterization of gut T cell precursors in euthymic and athymic mice....Pages 15-24
CRTH2: marker for the detection of human Th2 and Tc2 cells....Pages 25-29
GILZ, a glucocorticoid hormone induced gene, modulates T lymphocytes activation and death through interaction with NF-kB....Pages 31-39
Tyrosine phosphorylation of PICOT and its translocation to the nucleus in response of human T cells to oxidative stress....Pages 41-45
Front Matter....Pages 47-47
The molecular specificity of IgG-Fc interactions with Fcγ receptors....Pages 49-53
Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors....Pages 55-61
X-linked lymphoproliferative disease: the dark side of 2b4 function....Pages 63-67
Front Matter....Pages 69-69
Role of tapasin in MHC class I antigen presentation in vivo ....Pages 71-78
Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences....Pages 79-82
The AIR-1 encoded class II transactivator (CIITA): the master coordinator of MHC class II gene expression and ..more....Pages 83-91
Major histocompatibility complex class II (MHC II) expression during development of human fetal brain and haemopoietic organs....Pages 93-101
Interactions between dendritic cells....Pages 103-109
Neural regulation of dendritic cell function....Pages 111-119
A central role for heat shock proteins in host deficiency....Pages 121-126
Front Matter....Pages 127-127
Allele specific regulation of cytokine genes: Monoallelic expression of the IL-lA gene....Pages 129-139
Effect of polysaccharide sulfates on the production of interleukin-8 in an ex vivo model....Pages 141-144
Coordination of interleukin-6 biology by membrane bound and soluble receptors....Pages 145-151
Termination and modulation of IL-6-type cytokine signaling....Pages 153-160
Front Matter....Pages 127-127
Cytokine-induced STAT signalling through the cytoplasmic compartment....Pages 161-168
Cytokine-mediated growth inhibition of human melanoma cells....Pages 169-172
Interleukin-6, tumor necrosis factor α and interferon γ in patients with anorexia nervosa....Pages 173-176
Interleukin-1 system in testis — quantitative analysis....Pages 177-180
Front Matter....Pages 181-181
Mapping genes underlying complex disorders: progress on IgA deficiency and common variable immunodeficiency....Pages 183-190
Ataxia-Telangiectasia....Pages 191-198
Gene therapy of severe combined immunodeficiencies....Pages 199-204
Immune reconstitution after highly active antiretroviral treatment of HIV infection....Pages 205-212
Dissimilarity of clinical signs with parameters characterizing immune system....Pages 213-216
Front Matter....Pages 217-217
The role of Fc receptors and complement in autoimmunity....Pages 219-225
Effect of Hsp70-peptide complexes generated in vivo on modulation EAE....Pages 227-230
Gene transfer of protective cytokines in rheumatoid arthritis....Pages 231-240
Modification of humoral antisperm response....Pages 241-244
Front Matter....Pages 245-245
Immunologic mechanisms of allergen-specific immunotherapy....Pages 247-259
Phosphorothioate oligonucleotides: looking for the motif(s) possessing immunostimulatory activities in humans....Pages 261-264
Disorders in mononuclear phagocytes and reduced glutathione and their correction in Chernobyl children with recurrent respiratory infections and chronic inflammatory focal lesions....Pages 265-268
Front Matter....Pages 269-269
Adoptive transfer of mucosal T cells or dendritic cells from animals fed with cholera toxin B subunit alloantigen conjugate induces allogeneic T cell tolerance....Pages 271-275
Total body irradiation before bone marrow transplantation: aims and results....Pages 277-282
Statins as immunomodulatory drugs....Pages 283-288
Front Matter....Pages 289-289
Phage display of epitopes from HIV-1 elicits strong cytolytic responses in vitro and in vivo ....Pages 291-298
Front Matter....Pages 289-289
Oral Immunization of Human with transgenic lettuce Expressing Hepatitis B Surface Antigen....Pages 299-303
Nasal administration of Schistosoma Mansoni egg antigens-cholera toxin B subunit conjugate to infected mice reduces immunopathology and mortality....Pages 305-309
Anti-influenza vaccination changes expression of CD45 isoforms on peripheral blood NK cells of the elderly....Pages 311-314
Front Matter....Pages 315-315
Presence and functions of immune components in the tumor microenvironment....Pages 317-324
Expression of TCR ζ chain of tumor associated lymphocytes from malignant pleural effusions....Pages 325-329
Cytochrome c is rapidly extruded from apoptotic cells and detectable in serum of anticancer-drug treated tumor patients....Pages 331-334
CD 56 (N-CAM) antigen and mRNA expression in human endocrine glands....Pages 335-339
Front Matter....Pages 341-341
Glycodendrimeric ligands of C-type lectin receptors as therapeutic agents in experimental cancer....Pages 343-347
Exosomes in cancer immunotherapy: preclinical data....Pages 349-354
Bone marrow dendritic cell-based anticancer vaccines....Pages 355-358
Dendritic cell-based vaccines for therapy of HPV16-induced tumours....Pages 359-363
Cytokine gene transfection for autologous and allogeneic melanoma vaccines....Pages 365-368
Brain Tumor Treatment with IL-2 and IL-12 Producing Autologous Cancer Cell Vaccines....Pages 369-372
IL-11 is a potent anti-melanoma factor....Pages 373-377
IL-6 and GM-CSF in tumor rejection model of renal cell cancer....Pages 379-383
The effects of peritumoral therapeutic vaccination with IL-2-secreting cells on growth of MC38 colon tumours in mice, local NO production and sentinel lymph node cells activation....Pages 385-388
Improving the retroviral vector (RV) systems for immunotherapy of cancer....Pages 389-392
Tumor immunity in mice immunized with fibroblasts transfected with tumor DNA....Pages 393-401
T cell response to tumor antigens and its therapeutic use in cancer patients....Pages 403-410
Humoral responses to melanoma vaccine, genetically modified with interleukin 6 and soluble interleukin 6 receptor....Pages 411-418
Front Matter....Pages 341-341
Clinical studies of human papilloma vaccines in cervical cancer....Pages 419-427
Flow cytometric cytotoxicity assay with GFP gene modified target cells....Pages 429-434
Flow and video-imaging cytometry — usefulness of DNA ploidy measurements in diagnosis of malignant melanoma....Pages 435-438
Back Matter....Pages 439-442

✦ Subjects

Immunology; Oncology; Allergology; Hematology; Rheumatology