Th1 cells induce and Th2 inhibit antigen
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Francesco Ria; Giuseppe Penna; Luciano Adorini
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Article
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1998
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John Wiley and Sons
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English
β 301 KB
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Dendritic cells are the most relevant antigen-presenting cells (APC) for presentation of antigens administered in adjuvant to CD4 + T cells. Upon interaction with antigen-specific T cells, dendritic cells (DC) expressing appropriate peptide-MHC class II complexes secrete IL-12, a cytokine that drive