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Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

✍ Scribed by Jeroen N. Stoop; Rachel A. Harry; Alexei von Delwig; John D. Isaacs; John H. Robinson; Catharien M. U. Hilkens

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
330 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Abstract ## Objective We have demonstrated previously that dendritic cells (DCs) modified with immunosuppressive cytokines, and exosomes derived from DCs can suppress the onset of murine collagen‐induced arthritis (CIA) and reduce the severity of established arthritis. Indoleamine 2,3‐dioxygena