Prognostic value of the epidermal growth factor receptor (EGRF) and p53 in advanced head and neck squamous cell carcinoma patients treated with induction chemotherapy
✍ Scribed by Ricardo Hitt; Eva Ciruelos; María L. Amador; Amparo Benito; José J. Sanchez; Claudio Ballestin; Hernán Cortes-Funes
- Book ID
- 116428397
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 277 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0959-8049
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Epidermal growth factor (EGF) stimulates the growth of several types of epithelial tissues and possesses a strong mitogenic activity that is mediated through its cell surface receptor (EGFR). The aim of this study was to characterize EGFR and measure its levels in head and neck tumors biopsies (70 p
## Abstract The degree of gene amplification for epidermal growth factor receptor (EGFR) and its expression levels were examined in 4 cases of tumor lesions and their cell lines of human squamous cell carcinoma (SCC) of the oral cavity. The amplification was detected in 1 case (ZA), but not signifi