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Prognostic value of serum beta 2 microglobulin in primary gastric lymphoma

✍ Scribed by Agustin Avilés; José C. Díaz-Maqueo; Leticia Rodriguez; Edna L. García; Renaldo Guzmán; Alejandra Talavera

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
385 KB
Volume
9
Category
Article
ISSN
0278-0232

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✦ Synopsis

Sixty-eight previously untreated patients with primary gastric non-Hodgkin's lymphoma (NHL) available for analysis, were entered in a study in which the prognostic significance of serum beta 2 microglobulin levels were evaluated.

The serum beta 2 microglobulin was the most significant prognostic factor. Patients with high levels (> 3-5 pg/mL) had a relapse-free survival (RFS) of 36 months, while the median RFS has not been reached in patients with normal levels (P<O-OOl). The 5-year survival was 80 per cent for patients with normal levels, statistically significant when compared to patients with high levels: 38 per cent (p < 0.001).

Serum beta 2 microglobulin should be included in the initial staging of patients with primary extranodal NHL and patients with high levels should be treated more aggressively.

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