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Prognostic value of DNA ploidy in primary gastric leiomyosarcoma

✍ Scribed by Professor H. Suzuki; N. Sugihira


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
224 KB
Volume
80
Category
Article
ISSN
0007-1323

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✦ Synopsis


The prognostic value of DNA ploidy was evaluated in 25 patients with primary gastric leiomyosarcoma, using parafin-embedded archival specimens analysed by DNA $ow cytometry. Ploidy patterns were diploid in ten tumours and non-diploid in 15. They did not correlate with clinicopathological features of the lesions such as tumour size and grade or mitotic index. A non-diploid pattern was associated with a signiJicantly reduced patient survival rate (P < 0.05), as was higher tumour grade ( P < 0.01). Neither tumour size nor mitotic index correlated with patient survival.


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