Prognostic value of DNA ploidy in primary gastric leiomyosarcoma
β Scribed by Professor H. Suzuki; N. Sugihira
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 224 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0007-1323
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β¦ Synopsis
The prognostic value of DNA ploidy was evaluated in 25 patients with primary gastric leiomyosarcoma, using parafin-embedded archival specimens analysed by DNA $ow cytometry. Ploidy patterns were diploid in ten tumours and non-diploid in 15. They did not correlate with clinicopathological features of the lesions such as tumour size and grade or mitotic index. A non-diploid pattern was associated with a signiJicantly reduced patient survival rate (P < 0.05), as was higher tumour grade ( P < 0.01). Neither tumour size nor mitotic index correlated with patient survival.
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