Prognostic value of intrathecal antibody production and DNA viral load in cerebrospinal fluid of patients with herpes simplex encephalitis
✍ Scribed by Anders Hjalmarsson; Fredrik Granath; Marianne Forsgren; Maria Brytting; Paul Blomqvist; Birgit Sköldenberg
- Book ID
- 118297344
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 543 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0340-5354
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## Abstract A quantitative polymerase chain reaction (PCR) assay was evaluated retrospectively on 92 cerebrospinal fluid (CSF) samples from 29 patients with herpes simplex virus (HSV) encephalitis with the aim to study if the concentration of HSV genomes can be used as a prognostic marker and for m
Thirty-two cerebrospinal fluid (CSF) samples from eighteen patients with confirmed herpes simplex encephalitis (HSE) were assayed by an indirect enzyme-linked immunosorbent assay (ELISA) for the presence of viral antigens. The results are expressed as an antigen ratio distinguishing between herpes s
## Abstract Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV‐DNA was detected in the CSF of 13 patients with HSE, including 5 neona