## Abstract Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSVβDNA was detected in the CSF of 13 patients with HSE, including 5 neona
Rapid detection of herpes-simplex-virus DNA in cerebrospinal fluid of patients with herpes simplex encephalitis
β Scribed by Rowley, A.H.; Wolinsky, S.M.; Whitley, R.J.; Lakeman, F.D.
- Book ID
- 122594617
- Publisher
- The Lancet
- Year
- 1990
- Tongue
- English
- Weight
- 292 KB
- Volume
- 335
- Category
- Article
- ISSN
- 0140-6736
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Thirty-two cerebrospinal fluid (CSF) samples from eighteen patients with confirmed herpes simplex encephalitis (HSE) were assayed by an indirect enzyme-linked immunosorbent assay (ELISA) for the presence of viral antigens. The results are expressed as an antigen ratio distinguishing between herpes s
In a two-centre study, the routine DNA preparation and PCR amplification protocols were compared for herpes simplex virus (HSV) detection in cerebrospinal fluids (CSFs) of 43 patients with suspected herpes simplex encephalitis (HSE). The combined clinical, radiological and laboratory results indicat