Prognostic Value of 32P Uptake in Posterior Uveal Melanomas
β Scribed by McLean, Ian W.; Shields, Jerry A.
- Book ID
- 122208943
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 532 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0161-6420
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Malignant uveal melanoma is the commonest primary intraocular tumour in adults. It metastasizes frequently and 50% of patients die within 10 years of diagnosis. The expression of cyclin D1, p53, and MDM2 in uveal melanoma and their relationship to metastasis-free 5-year survival was determined, in o
## Abstract Six posterior uveal melanomas were karyotyped after shortβterm culture. One had a normal chromosome complement; the remaining five had limited chromosome changes. Involvement of chromosomes 1 and 6 was noted in two and four cases, respectively, and three ciliary body tumours demonstrate