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Prognostic significance ofFLT3internal tandem duplication andNPM1mutations in acute myeloid leukemia in an unselected patient population

✍ Scribed by Rikio Suzuki, Makoto Onizuka, Minoru Kojima…

Book ID: 120955011
Publisher: Carden Jennings Publishing
Year: 2007
Tongue: English
Weight: 121 KB
Volume: 86
Category: Article
ISSN: 0925-5710
DOI: 10.1007/BF02984000

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## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte