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Prognostic significance of serum p53 antibody in patients with esophageal squamous cell carcinoma

✍ Scribed by Shimada, Hideaki; Nabeya, Yoshihiro; Okazumi, Shin-ichi; Matsubara, Hisahiro; Funami, Yutaka; Shiratori, Tooru; Hayashi, Hideki; Takeda, Akihiko; Ochiai, Takenori


Book ID
122356088
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
77 KB
Volume
132
Category
Article
ISSN
0039-6060

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## Background and objectives: It is generally accepted that the overexpression of p53 protein is associated with poor prognosis in breast, colorectal, and other types of cancer. however, the prognostic significance of p53 aberrations in esophageal squamous cell carcinoma has yet to be determined. w

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## Abstract ## Objectives This study aims at investigating the prognostic values of serum p53 protein and anti‐p53 antibody in patients undergoing surgical treatment for head and neck squamous cell carcinoma (HNSCC). ## Methods Serum p53 protein and anti‐p53 antibody concentrations were determin