Prognostic Significance of Gremlin1 (GREM1) Promoter CpG Island Hypermethylation in Clear Cell Renal Cell Carcinoma
✍ Scribed by Iris J.H. van Vlodrop; Marcella M.L. Baldewijns; Kim M. Smits; Leo J. Schouten; Leander van Neste; Wim van Criekinge; Hein van Poppel; Evelyne Lerut; Kornel E. Schuebel; Nita Ahuja; James G. Herman; Adriaan P. de Bruïne; Manon van Engeland
- Book ID
- 117971045
- Publisher
- American Society for Investigative Pathology
- Year
- 2010
- Tongue
- English
- Weight
- 461 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0002-9440
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Renal clear cell carcinoma (RCCC) is a malignant tumor with poor prognosis caused by the high incidence of metastasis to distal organs. Although metastatic RCCC cells frequently show aberrant cytoskeletal organization, the underlying mechanism has not been elucidated. DAL‐1/4.1B is an a
Homozygous deletion and loss of heterozygosity (LOH) at chromosome 3p21 have been observed in several types of human cancer including lung cancer and breast cancer. In previous work, we cloned and identified the human RAS association domain family 1A gene (RASSF1A) from the lung tumor suppressor loc