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Prognostic significance of dna ploidy in carcinoma of prostate

✍ Scribed by Stephen W. Dejter Jr.; Robert E. Cunningham; Philip D. Noguchi; Robert V. Jones; Judd W. Moul; David G. McLeod; John H. Lynch


Book ID
119046352
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
668 KB
Volume
33
Category
Article
ISSN
0090-4295

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DNA-ploidy in 143 cases of prostatic carcinoma was assessed by flow cytometric analysis of paraffin-embedded biopsy material. The majority of the tumours (64.3%) were diploid, but in advanced sta es the DNA-aneuploidy rate increased from 15 to over 604. No hypoploid tumour was observed and most of t

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Background. DNA ploidy pattern is sometimes used as a prognostic factor. Heterogeneity of a tumor could, however, give false information when a single analysis is performed. Methods. Twenty-eight patients with adenoid cystic carcinomas were retrospectively studied with regard to clinicohistologic p