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Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells

✍ Scribed by Tao, Hiroyuki; Mimura, Yusuke; Aoe, Keisuke; Kobayashi, Seiki; Yamamoto, Hiromasa; Matsuda, Eisuke; Okabe, Kazunori; Matsumoto, Tsuneo; Sugi, Kazurou; Ueoka, Hiroshi


Book ID
119320637
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
588 KB
Volume
75
Category
Article
ISSN
0169-5002

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Regulatory T cells (T reg ) inhibit the generation of host-versus-tumor immunity via suppression of tumor-specific effector T-cell responses and development of immune tolerance to neoplastic cells. The transcription factor forkhead box P3 (FOXP3) is an intracellular key molecule for T reg developmen