Lymphokine-activated killer (LAK) cell activity of peripheral blood mononuclear cells (PBM), spleen cells (SPC), regional lymph node cells (LNC), and tumor-infiltrating lymphocytes (TIL), induced by activation with interleukin 2 (IL 2) for 4 days, was evaluated in patients with gastric carcinoma. TI
Distribution of Th17 cells and FoxP3(+) regulatory T cells in tumor-infiltrating lymphocytes, tumor-draining lymph nodes and peripheral blood lymphocytes in patients with gastric cancer
β Scribed by Takanori Maruyama; Koji Kono; Yoshiki Mizukami; Yoshihiko Kawaguchi; Kousaku Mimura; Mitsuaki Watanabe; Shinichirou Izawa; Hideki Fujii
- Book ID
- 108586783
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 350 KB
- Volume
- 101
- Category
- Article
- ISSN
- 1347-9032
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Publication of the International Union Against Cancer Publication de i'Union lnternationale Contre le Cancer
Regulatory T cells (T reg ) inhibit the generation of host-versus-tumor immunity via suppression of tumor-specific effector T-cell responses and development of immune tolerance to neoplastic cells. The transcription factor forkhead box P3 (FOXP3) is an intracellular key molecule for T reg developmen
## Abstract It has been reported that an increased population of regulatory T cells (Tregs) is one of the reasons for impaired antiβtumor immunity. Recently, Foxp3 has been reported as a reliable marker of Tregs. The authors investigated the frequency of Foxp3^+^ Tregs within CD4^+^ cells in TILs,