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Prognostic markers and putative therapeutic targets for hepatocellular carcinoma

✍ Scribed by Maddalena Frau; Fiorella Biasi; Francesco Feo; Rosa M. Pascale

Book ID
118485876
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
568 KB
Volume
31
Category
Article
ISSN
0098-2997

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## Abstract Degradation of extracellular matrix is crucial for malignant tumour growth, invasion, metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc‐dependent neutral endopeptidases collectively capable of degrading essentially all matrix components. Elevated levels