We report on the screening of the entire BRCA1/BRCA2 coding sequence by SSCP, PTT, and direct sequencing in 68 Italian families with recurrent breast or ovarian cancer. For each investigated proband, the probability of being carrier of a BRCA1/BRCA2 mutation was evaluated using the BRCAPRO software.
Prognostic impact of BRCA1 pathogenic and BRCA1/BRCA2 unclassified variant mutations in patients with ovarian carcinoma
β Scribed by Ewa Joanna Majdak; Jaroslaw Debniak; Tomasz Milczek; Cees J. Cornelisse; Peter Devilee; Janusz Emerich; Jacek Jassem; Geertruida Hendrika De Bock
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 213 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0008-543X
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