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BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases

✍ Scribed by Tuya Pal; Jenny Permuth-Wey; Judith A. Betts; Jeffrey P. Krischer; James Fiorica; Hector Arango; James LaPolla; Mitchell Hoffman; Martin A. Martino; Katie Wakeley; George Wilbanks; Santo Nicosia; Alan Cantor; Rebecca Sutphen


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
107 KB
Volume
104
Category
Article
ISSN
0008-543X

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Ovarian cancer is a clinically important cancer in Turkey. The contribution of BRCA1 and BRCA2 to ovarian cancer in Turkish patients has not previously been described. In this study we investigated the presence of BRCA1 and BRCA2 mutations in 102 consecutively ascertained, hospital-based, ovarian ca