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Prognostic factors in AML in relation to (ab)normal karyotype

✍ Scribed by Richard M. Stone


Book ID
116305152
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
118 KB
Volume
22
Category
Article
ISSN
1521-6926

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## Abstract Cytogenetic abnormalities are among the most important factors affecting the outcome of patients with acute myeloid leukaemia (AML), but approximately 40–50% of AML cases display a normal karyotype at diagnosis. Multidrug resistance (MDR) proteins overexpression is associated with worse