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Prognostic factors for the malignant triton tumor of the head and neck

✍ Scribed by Andrej Terzic; Beata Bode; Klaus W. Gratz; Sandro J. Stoeckli

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 169 KB
Volume: 31
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.21051

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

Malignant triton tumors are rare neoplasias consisting of a malignant peripheral nerve sheath tumor with additional rhabdomyoblastic differentiation. These tumors are highly aggressive and prognosis is poor. Our aim is to describe the outcome and to identify potential prognostic factors.

Methods.

From 1993 to 2005, 7 patients with a malignant triton tumor of the head and neck were treated at our institution. A literature search revealed another 46 published cases. All these cases were analyzed for outcome and prognostic factors.

Results.

Patients with primary tumors involving the nose and paranasal sinuses have better, patients involving the neck a poor prognosis. All other locations show an intermediate course. Complete surgical removal is of crucial importance. Additional radiation or chemotherapy show little effect.

Conclusion.

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