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Progestin regulation of 11β-hydroxysteroid dehydrogenase expression in T-47D human breast cancer cells

✍ Scribed by Felice Arcuri; Silvia Sestini; Claudia Ricci; Ylenia Runci; Antonietta Carducci; Luana Paulesu; Marcella Cintorino

Book ID
117667996
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
248 KB
Volume
72
Category
Article
ISSN
0960-0760

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✍ M. Poutanen; V. Isomaa; K. Kainulainen; R. Vihko 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 643 KB

## Abstract Steroid regulation of 17β‐hydroxysteroid dehydrogenase (17‐HSD) was studied in the T‐47D human breast‐cancer cell line, using a radioimmunoassay. In addition, 3 mRNA species (2.4, 1.4, and 0.9 kb) specific for the enzyme were shown to be present in these cells. All the synthetic progest