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Progesterone receptor polymorphisms and risk of breast cancer: results from two Australian breast cancer studies

✍ Scribed by Sharon E. Johnatty; Amanda B. Spurdle; Jonathan Beesley; Xiaoqing Chen; John L. Hopper; David L. Duffy; Georgia Chenevix-Trench; The Kathleen Cuningham Consortium for Research in Familial Breast Cancer

Publisher
Springer US
Year
2007
Tongue
English
Weight
192 KB
Volume
109
Category
Article
ISSN
0167-6806

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## Abstract Estrogens, and to a lesser extent progesterones, influence the proliferation, differentiation and physiology of breast tissue as well as the development and progression of breast cancer. Genetic variants in the steroid hormone receptor genes __ESR1__ and __PGR__ (belonging to the nuclea