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Progesterone Enhancement of Stomach Tumor Development in SD Rats Treated withN-Methyl-N'-nitro-N-nitrosoguanidine

✍ Scribed by Ando, Yasumi ;Watanabe, Hiromitsu ;Fujimoto, Nariaki ;Ito, Akihiro ;Toge, Tetsuya

Book ID: 108581036
Publisher: Wiley (Blackwell Publishing)
Year: 1995
Tongue: English
Weight: 288 KB
Volume: 86
Category: Article
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1995.tb03002.x

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The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitroroguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 5 I 2 mg/kg body weight, every other day after 20 weeks of or