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Profound and Selective Loss of Catalytic TrkB Immunoreactivity in Alzheimer's Disease

✍ Scribed by Shelley J. Allen; Gordon K. Wilcock; David Dawbarn


Book ID
115584657
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
90 KB
Volume
264
Category
Article
ISSN
0006-291X

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Loss of neurons from the substantia nigra (SN), which is sometimes observed in Alzheimer's disease (AD), was quantitatively analyzed in 10 cases of presenile AD and 19 age-matched controls. On sections from the upper and lower portions of the SN, the pigmented zone (zona compacta) and the non-pigmen