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Profiling two indole-2-carboxamides for allosteric modulation of the CB1 receptor

โœ Scribed by Ahn, Kwang H.; Mahmoud, Mariam M.; Samala, Sushma; Lu, Dai; Kendall, Debra A.

Book ID
120057544
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
407 KB
Volume
124
Category
Article
ISSN
0022-3042

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## Abstract The cannabinoid CB~1~ receptor is a class A G proteinโ€coupled receptor (GPCR) that is the most widely expressed GPCR in the brain. Many GPCRs contain allosteric binding sites for endogenous and/or synthetic ligands, which are topographically distinct from the agonistโ€binding site that i