Profile of p53 expressions in human tissue biopsies of bladder and head and neck tumours: Effects of various in vitro manipulations of p53 on tumour cell behaviour in vitro
β Scribed by A.M.E. Nouri; H. Cannell; R.T.D. Oliver
- Book ID
- 117658260
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 343 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0959-8049
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Mutation of the p53 tumor suppressor gene has been demonstrated in a large proportion of human head and neck squamous cell carcinomas (HNSCCs) and has been assumed to play a role in the pathogenesis of these tumors, although no formal evidence of functional aberration has been demonstrated. In this
## Abstract ## Background. Although cyclooxygenaseβ2 (COXβ2) has been suggested to play an important role in carcinogenesis, the effects of tumor suppressors on COXβ2 gene expression and the combined antitumor effects of tumor suppressors and COXβ2 inhibitors have rarely been investigated. ## Met