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During the 1939-45 war when Czech universities were closed, he worked as a scientific officer in the laboratory of a Prague hospital. Strangely enough, these years were his most fruitful. Soon after the war he was appointed Professor of Physical Chemistry and in 1950 became Heyrovskjr's successor as Head of the Department of Physical Chemistry of the Charles University. From 1954 he was Director of the Institute of Physical Chemistry of the Czechoslovak Academy of Sciences.
Brdicka's scientific field was electrochemistry, with approaches to reaction kinetics and biochemistry.
His experimental technique was mainly polarography. In pre-war time his principal contribution was the discovery of the catalytic hydrogen evolution on mercury electrodes in ammonia buffer solutions containing cobaltous ions and free or peptidically bound aminoacids with a sulphydryl or disulphide group (cysteine, for example). This finding became the basis of a remarkable method in protein analysis [R. BrdiEka, Research 1, 25 (194711. During the war he initiated
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