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Professional Memory CD4+ T Lymphocytes Preferentially Reside and Rest in the Bone Marrow

✍ Scribed by Koji Tokoyoda; Sandra Zehentmeier; Ahmed N. Hegazy; Inka Albrecht; Joachim R. Grün; Max Löhning; Andreas Radbruch


Book ID
108152499
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
709 KB
Volume
30
Category
Article
ISSN
1074-7613

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## Abstract CMV‐specific CD8^+^ T cell responses in peripheral blood (PB) are characterized by a preponderance of effector and effector memory T cells. CMV‐specific central memory T cells (T~CM~), which are considered crucial in maintaining long‐term immunity, are rarely detectable in PB. In this s