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Production of recombinant proteins in fermenter cultures of the yeast Pichia pastoris

✍ Scribed by Geoff P.Lin Cereghino; Joan Lin Cereghino; Christine Ilgen; James M Cregg

Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
86 KB
Volume
13
Category
Article
ISSN
0958-1669

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✦ Synopsis

The Pichia pastoris expression system offers economy, ease of manipulation, the ability to perform complex post-translational modifications, and high expression levels. Using this system, recent advances have been made in the quality of recombinant proteins in fermenter culture and in the quality of the protein product, namely improved secretion signals and glycosylation patterns.

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