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Production of Platelet-Derived Endothelial Cell Growth Factor by Normal and Transformed Human Cells in Culture

โœ Scribed by Kensuke Usuki, Nils-Erik Heldin, Kohei Miyazono, Fuyuki Ishikawa, Fumimaro Takaku, Bengt Westermark and Carl-Henrik Heldin

Book ID
123745597
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
946 KB
Volume
86
Category
Article
ISSN
0027-8424

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Production of platelet-derived growth fa
Production of platelet-derived growth factor by cultured Wilms' tumor cells and fetal kidney cells
โœ Dr. Gail E. Fraizer; Daniel F. Bowen-Pope; Dr. Arthur M. Vogel ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 694 KB

We have cultured human Wilms' tumors (nephroblastomas) in vitro and examined their growth properties, tumorigenicity in nude mice, karyotypes, and production of a platelet-derived growth factor (PDGF)-like activity (PDGF,). The cultured Wilms' tumor cells do not exhibit transformed growth properties