Production of monoclonal antibody to characterize the antigen ofParagonimus westermani
β Scribed by H. Sugiyama; H. Hinoue; J. Katahira; T. Horiuchi; T. Tomimura; Y. Kamata; S. Kozaki
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 1024 KB
- Volume
- 75
- Category
- Article
- ISSN
- 1432-1955
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Monoclonal antibodies (MAbs) were prepared to a synthetic peptide (PI : I I94 40 amino acids) in domain I of the carcinoembryonic antigen (CEA) molecule. The majority of the amino acids in peptide P I show a hydrophilic character, and similar sequences are repeated in domains I, II and 111 of this m
## Abstract Seven monoclonal antibodies were raised against the immunoglobulinβlike extracellular domain of P0 (P0βED), the major protein of peripheral nervous system myelin. Mice were immunized with purified recombinant rat P0βED. After fusion, 7 clones (P01βP07) recognizing either recombinant, ra