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Production of monoclonal antibodies to P-glycoprotein: its application in detection of soluble and surface P-glycoprotein of leukemia patients

โœ Scribed by Sawitree Chiampanichayakul; Songyot Anuchapreeda; Nuttapol Chruewkamlow; Kodchakorn Mahasongkram; Pattra Thanaratanakorn; Watchara Kasinrerk


Book ID
107619118
Publisher
Carden Jennings Publishing
Year
2010
Tongue
English
Weight
394 KB
Volume
92
Category
Article
ISSN
0925-5710

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Immunohistochemical detection of P-glyco
โœ Hemmer, Michael J. ;Courtney, Lee A. ;Ortego, Lisa S. ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 991 KB

Mammalian P-glycoprotein is a highly conserved 170-kD integral plasma membrane protein functioning as an energy-dependent efflux pump of exogenous and endogenous lipophilic aromatic compounds entering the cell by diffusion. In this study, the tissue specificities of one polyclonal (pAb) and three mo