Elimination of by-products in 11β-hydrox
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Danuta Wilmańska; Krystyna Milczarek; Anna Rumijowska; Katarzyna Bartnicka; Leon
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Article
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1992
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Springer
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English
⚖ 500 KB
Stable mutants showing improved 11-hydroxylation of Substance S were isolated, following treatment with N-methyl-N'-nitro-N-nitrosoguanidine (NTG) and regeneration of uninucleate protoplasts of the appropriate fungal strains. This procedure was especially suitable for obtaining more directed 11 beta