## Abstract For Abstract see ChemInform Abstract in Full Text.
Production of a Soluble Cyclin B/cdc2 Substrate for cdc25 Phosphatase
โ Scribed by J.M. Clark; B.G. Gabrielli
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 243 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Cdc25A is a dual-specific protein phosphatase involved in the regulation of the kinase activity of Cdk-cyclin complexes in the eukaryotic cell cycle. To understand the mechanism of this important regulator, we have generated highly purified biochemical reagents to determine the kinetic constants for
## Abstract Immortalization of rodent cells by oncogenes is a complex biological process which involves the abnormal regulation of genes who control cellular proliferation. The role of the cell cycle control genes cdc2, cdc25 and cyclin A in the maintenance of immortalization and in growth arrest w