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Production of a Secreted Glycoprotein from an Inducible Promoter System in a Perfusion Bioreactor

✍ Scribed by Matthew L. Lipscomb; Mark C. Mowry; Dhinakar S. Kompala

Book ID
109387206
Publisher
American Institute of Chemical Engineers
Year
2004
Tongue
English
Weight
108 KB
Volume
20
Category
Article
ISSN
8756-7938

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A nar promoter system (a modified nar promoter in a mutant host Escherichia coli (pMW618/W3110narL(-))), which is maximally induced under microaerobic conditions, was developed and characterized through batch and fed-batch culture to see whether the modified nar promoter can be used as an oxygen-dep