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Production and Characterization of Hot-Melt Extruded Films Containing Clotrimazole

✍ Scribed by Repka, Michael A.; Prodduturi, Suneela; Stodghill, Steven P.

Book ID
111645663
Publisher
Informa plc
Year
2003
Tongue
English
Weight
331 KB
Volume
29
Category
Article
ISSN
0363-9045

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Poly(ethylene oxide) (PEO) was used to prepare thin polymer films containing clotrimazole (CT) utilizing hot-melt extrusion (HME) technology. Films containing PEOs of two different molecular weights and the drug were investigated for solidstate characteristics, moisture-sorption, bioadhesivity, mech