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Production and characterization of antibody blocking epidermal growth factor: Receptor interactions

✍ Scribed by Harry T. Haigler; Graham Carpenter

Book ID: 115724428
Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 711 KB
Volume: 598
Category: Article
ISSN: 0005-2736
DOI: 10.1016/0005-2736(80)90009-7

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## Abstract A monoclonal antibody of the IgG class, EGFR1, has been isolated using cells of the epidermoid carcinoma line A431 as immunogen. The A431 antigen recognized by EGFR1 has an apparent molecular weight of approximately 175,000, is a cell‐surface molecule which can be specifically cross‐lin