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Product stereospecificity in the microbial reductions of hydroaromatic ketones

✍ Scribed by Kabuto, Kuninobu; Imuta, Mitsuru; Kempner, Ellis S.; Ziffer, Herman


Book ID
126887490
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
713 KB
Volume
43
Category
Article
ISSN
0022-3263

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Various microorganisms can be used to reduce ketoimidazole 3 to hydroxyimidazole 4. contrast, Only one enantiomer (i.e., (R)-4) is produced. In ketoimidazolium salt 2 is not reduced uiider identical conditions. The importance of racemic imidazolium salt 1 as an active Class III antiarrhythmic agent