Prochiral sulfide probes for the active-
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Michael B. Fisher; Allan E. Rettie
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Article
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1997
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Elsevier Science
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English
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Mammalian flavin-containing monooxygenases are known to oxygenate prochiral sulfides often with a high degree of stereoselectivity. In the present study we used two homologous series of n-alkyl aryl sulfides, Ar-S-(CH2)nH, (where Ar=p-tolyl or 2-naphthyl and n=l-7), to probe the active site topograp