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Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system

โœ Scribed by Ireland, Jamie M.; Unanue, Emil R.


Book ID
111870353
Publisher
Landes Bioscience
Year
2012
Tongue
English
Weight
445 KB
Volume
8
Category
Article
ISSN
1554-8627

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T cell-recognized antigenic peptides der
โœ Thierry Boon; Aline Pel ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 644 KB

It is now widely accepted that cytolytic T cells recognize their antigens in the form of small peptides bound to major histocompatibility complex molecules at the surface of the target cells. We present here the hypothesis that, when these antigenic peptides are derived from the cellular genome, the