An enantioselective iodine/magnesium exchange reaction between the diiodoalkane 4 and a chiral Grignard reagent 12 has been realized at À 78 8C in THF. The resulting a-iodoalkylmagnesium reagents 13 are configurationally stable under these conditions and during trapping by a benzaldehyde/dimethylalu
✦ LIBER ✦
Process Safety Evaluation of a Magnesium−Iodine Exchange Reaction
✍ Scribed by Reeves, Jonathan T.; Sarvestani, Max; Song, Jinhua J.; Tan, Zhulin; Nummy, Laurence J.; Lee, Heewon; Yee, Nathan K.; Senanayake, Chris H.
- Book ID
- 118116104
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 306 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1083-6160
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