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Process Research on the Preparation of 1-(3-Trimethylsilylphenyl)-2,2,2-trifluoroethanone by a Friedel–Crafts acylation Reaction

✍ Scribed by Wolf, Richard A.


Book ID
124091709
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
136 KB
Volume
12
Category
Article
ISSN
1083-6160

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Double Friedel–Crafts Acylation Reaction
✍ Dr. Duncan Carmichael; Prof. Dr. Pascal Le Floch; Dr. Xavier F. Le Goff; Dr. Oli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 667 KB

## Abstract The synthetic outcome of the Friedel–Crafts acylation of 1′,2′,3,3′,4,4′,5′‐heptamethylphospharuthenocene reflects the nature of the acylating agent, with alkanoyl anhydride/trifluoromethanesulfonic acid (TfOH) reagents giving monosubstitution at the phospholyl ring, whereas alkanoyl ch