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Procarbazine hypersensitivity manifested as a fixed drug eruption

โœ Scribed by Giguere, Jeffrey K. ;Douglas, Danny M. ;Lupton, George P. ;Baker, James R. ;Weiss, Raymond B.


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
345 KB
Volume
16
Category
Article
ISSN
0098-1532

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โœฆ Synopsis


A case of a previously unrecognized form of hypersensitivity to procarbazine characterized by a nonpigmented fixed drug eruption is reported. Despite skin testing, association of the skin lesion to procarbazine could be determined only by drug rechallenge. Various aspects of procarbazine hypersensitivity reactions as well as the pathogenesis and importance of the fixed drug eruption are discussed.


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