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Probucol in the treatment of non-alcoholic steatohepatitis: a double-blind randomized controlled study

โœ Scribed by Shahin Merat; Reza Malekzadeh; Masoud Reza Sohrabi; Masoud Sotoudeh; Nasser Rakhshani; Amir Ali Sohrabpour; Siavosh Naserimoghadam


Book ID
118564907
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
96 KB
Volume
38
Category
Article
ISSN
0168-8278

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In nonalcoholic steatohepatitis (NASH), the extent of hepatocyte apoptosis correlates with disease severity. Reducing hepatocyte apoptosis with the selective caspase inhibitor GS-9450 has a potential for altering the course of the liver disease. In this phase 2, double-blind study, 124 subjects with