Problems encountered in measuring erythrocyte pyrimidine 5′-nucleotidase activity
✍ Scribed by John D. Torrance; Michael S. Wulfsohn; Wendy Mills
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 349 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0003-2697
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📜 SIMILAR VOLUMES
Inhibition by lead of erythrocyte pyrimidine 5'-nucleotidase (P5N) is thought to contribute to morphological abnormalities observed in red blood cells (RBC) of lead-exposed subjects. However, neither the mechanism of lead inhibition of P5N nor the relationship of this inhibition to blood lead levels
## Abstract A micellar electrokinetic chromatographic method that allows simultaneous determination of both nucleotidase and transferase activities of cytosolic 5'‐nucleotidase III is presented. This electrophoretic approach was successfully applied to human erythrocyte lysates to monitor the enzym